The Human Papillomavirus and Its Relationship to Infertility and Endometriosis

Background: The pathogenesis of endometriosis is still debatable, and many studies reported a predisposition to infectious immunological factors. In this study, we aimed evaluate the human papillomavirus (HPV) positivity in pain-related symptoms infertility. Methods: cross-sectional 410 patients were enrolled study. HPV-positive (n = 202) HPV-negative 208) compared with symptoms, infertility, endometrioma presence. term “Other HPV” was utilized encompass all HPV types exception 16 18, which specifically identified as 16/18. Results: Dyspareunia HPV”-positive group (12.8 %) statistically higher than (4.8%; p 0.007). infertility rate significantly 16/18 positive (high-risk HPV) 35.8% (7.6%), (8%; < 0.001). Endometriosis-related pain high-risk (49%) (37%), (46.3%; 0.046). ovarian slightly population (16.9%) (11.4%), groups (7.2%; 0.08). Conclusions: Our results could provide potential predisposing role infection clinics Moreover, subtypes may have different impact on clinical conditions.